Browsing by Author "Danylchenko S. I."

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ƏZİZ MƏMMƏDKƏRİM OĞLU ƏLİYEV
(2025) Burdina V. R.; Danylchenko S. I.
COMPREHENSIVE REHABILITATION OF OLDER ADULTS FOLLOWING ACUTE STROKE: EMPHASIS ON THERAPEUTIC EXERCISES AND THE MULTIDISCIPLINARY APPROACH
(2025) Salii A. O.; Danylchenko S. I.; Golovchenko I. V.; Tarasova O. O.; Morozenko D. V.
Background. Stroke remains one of the leading causes of long-term disability worldwide, especially among older adults. Given the increasing incidence of CerebroVascular Accidents (CVAs) in the aging population, there is a growing need for comprehensive, individualized reha- bilitation programs that address the specific physical, cognitive, and emotional needs of elderly patients. Aim. To evaluate the effectiveness of therapeutic exercise as part of a multidisciplinary reha- bilitation approach in elderly patients following an acute stroke. Materials and Methods. The study included 21 patients aged 62 to 79 years who were under- going rehabilitation following an acute CVAs in a district hospital setting. The rehabilitation pro- cess featured a seven-stage individualized program consisting of physical therapy, occupational therapy, speech and language therapy, cognitive training, and psychosocial support. The effec- tiveness of the interventions was evaluated using standardized scales: the Modified Rankin Scale, Barthel Index, Montreal Cognitive Assessment, Visual Analogue Scale, and Borg Rating of Per- ceived Exertion. Results. 76% of the participants (n=16) showed significant improvement in their overall con- dition, including reduced neurological symptoms (aphasia, hemiplegia), enhanced motor skills, better balance, improved emotional well-being, and increased independence in daily activities. The remaining 24% of patients (n=5) also demonstrated positive changes but required additional rehabilitation cycles due to limited recovery potential and complex comorbidities. Conclusions. Individualized therapeutic exercises, integrated within a multidisciplinary reha- bilitation framework, are effective in improving the physical and cognitive outcomes of elderly patients after stroke. Early initiation of rehabilitation, combined with continuous assessment and support from a multidisciplinary team, enhances functional recovery and improves the overall quality of life in this vulnerable population.
HOW ARTICLES ARE PREPARED FOR PUBLICATION IN THE SCIENTIFIC JOURNALS OF THE KHARKIV NATIONAL
(2025) Nakonechna O. A.; Shevchenko A. S.; Danylchenko S. I.; Korneiko I. V.
Kharkiv National Medical University (KhNMU) is the founder and publisher of periodical (quarterly) peer-reviewed scientific journals of open access "Medicine Today and Tomorrow" (ISSN print 2414-4495, ISSN online 2710-1444), "Experimental and Clinical Medicine" (ISSN print 2414-4517, ISSN online 2710-1487) and "Inter Collegas" (ISSN online 2409- 9988). We have analyzed the work with manuscripts of articles of these journals and present readers with a detailed description of the procedures that should help the authors of articles to effectively cooperate with the editors of these scientific journals in preparing their articles for publication. The article will also be useful to members of editorial boards and editorial councils of journals. This publication will help article reviewers determine their readiness for the procedure. We described both the existing rules and procedures for working with manu- scripts, as well as the changes that will come into force from the beginning of July 2025. The article describes the structure of the manuscript, issues of ethics of the researcher and author, copyright, plagiarism checking, reviewing and editing of manuscripts, the policy of the jour- nal in cases of violation of ethics, the mission of the journals. The editorial board uses a double blinded peer review procedure with the participation of at least two reviewers for each article. Reviewers are invited by editors. The reviewers have the appropriate specialization and ex- perience in the subject matter of the articles they propose. The editorial board is loyal to the lack of experience of young authors, but is intolerant of falsification of research results and plagiarism, creating conflict situations while working on manuscripts. The publication of ar- ticles and their further use is under the terms of the Creative Commons license (BY-NC-SA). The editorial board relies on the principles of evidence-based medicine and publishes articles that contain contradictory issues from the point of view of evidence with a note about their disagreement with the position of the authors.
INTEGRATION OF PSYCHOLOGICAL REHABILITATION INTO THE PHYSICAL THERAPY SYSTEM FOR MILITARY PERSONNEL AFTER AMPUTATION
(2025) Tkachuk A.V.; Danylchenko S. I.; Babkina O. P.; Golovchenko I. V.; Korsunskyy O.Yu.
Since the beginning of the full-scale war in Ukraine in 2022, the issue of rehabilitation for military personnel has become particularly relevant. Medical rehabilitation for service members includes a range of measures aimed at restoring physical health after injuries and wounds, as well as addressing post- traumatic stress disorder. The aim of this study is to analyze the role of psychological support in the process of physical rehabilitation of military patients after limb amputation who show signs of post-traumatic stress disorder. Materials and Methods. The study focuses on the rehabilitation process of military personnel after limb amputation accompanied by post-traumatic stress disorder, based on the analysis of scientific literature related to psychophysical rehabilitation, psychological support, and physical therapy for service members. Results. Psychological assessment of military personnel who have undergone limb amputation and prosthetic fitting is a critical stage in their rehabilitation process. Such assessment allows for the identification of post-traumatic stress disorder, depression, and other psycho-emotional conditions that may complicate the adaptation to a new way of life. This diagnostic process is aimed at detecting and evaluating these psychological states, which can affect the effectiveness of recovery and the overall well-being of the patient. Psychological evaluation is an integral part of the rehabilitation process for amputee veterans. It provides a deep understanding of the patient’s emotional state and enables the development of an individualized support plan aimed at optimal recovery and improved quality of life. Resocialization of military personnel after amputation involves returning to active social life and professional activity. This may include vocational retraining, participation in community events, and support in maintaining or re-establishing social connections. Conclusion. A comprehensive approach to the rehabilitation of military personnel after limb amputation includes physical therapy, psychological support, and resocialization measures. These components together contribute to full recovery and reintegration into active life. Psychological support enhances self-esteem, life satisfaction, and overall social functioning.
LABORATORY MARKERS FOR OVERLOAD OF THE CERVICAL SPINE
(2025) Leontieva F. S.; Fedotova I. F.; Morozenko D. V.; Danylchenko S. I.
Recently, the number of applications from patients who have significant physical exertion in conditions of prolonged exposure to stress factors has increased significantly. Spinal overload is a rather serious and important factor that contributes to the development of degenerative changes, as well as metabolic disorders of various kinds that occur in conditions of chronic stress. In clinical and fundamental medicine, most of the clinical and pathophysiological changes in the human body that occur under the influence of chronic stress and contribute to the development of metabolic disorders during spinal overload remain incompletely understood. This problem is especially important and relevant today for the military, who, during the difficult fight against armed aggression in conditions of chronic stress, have significant physical exertion, which is reflected in the condition of the spine. The aim of the study is to identify the most modern laboratory markers of metabolic disorders during spinal overload. Materials and methods. The scientific data of the PubMed platform for 2021– 2025 were analysed. Results The dynamics of clinical and functional disorders in the body of patients with cervical spine overload on the background of chronic stress includes a complex of structural, functional changes and neurological disorders, which in the case of a long course lead to the development of degenerative diseases of the spine. The conceptual scheme of the formation of metabolic disorders in patients with cervical spine overload on the background of chronic stress consists in the consistent and gradual development of clinical and metabolic disorders, which are reflected in structural and functional changes and clinical and laboratory indicators of blood and urine. The direction of research on the development of criteria for assessing and preventing the impact of chronic stress on the human body with spinal overload can be considered promising. Among the most informative markers that can be used to examine patients are the following: C-reactive protein (may increase in the blood due to inflammation of muscle tissue and/or ligaments in the neck area), integral leukogram indicators (changes in the ratio of leukocytes – leukocytosis, lymphocytopenia or neutrophilia may be detected in patients as reactions to stress); interleukin-1 (often increases in the blood during chronic stress and is associated with inflammation), as well as interleukin- 10 (has an anti-inflammatory effect and may decrease during chronic stress). Conclusions. The most effective laboratory markers for assessing the condition of patients with cervical spine overload on the background of chronic stress can be considered inflammatory markers, marker enzymes for assessing muscle tissue, indicators of insulin resistance, hormonal metabolism and interleukins.
PERSONALIZED REHABILITATION STRATEGIES FOLLOWING LOWER LIMB AMPUTATION: CLINICAL AND FUNCTIONAL OUTCOMES
(2025) Danylenko A. S.; Danylchenko S. I.; Fursenko A. О.; Morozenko D. V.; Chorna I. O.
Objective. The objective of this study was to evaluate the effectiveness of a physical rehabilitation protocol for patients following lower limb amputation, taking into account prosthetic fitting specifics and gait skill development. Materials and Methods. The study included 20 patients with transtibial amputations. The rehabilitation program integrated therapeutic exercise, physiotherapy, massage, robotic-assisted technologies, and psychological support. Effectiveness was assessed using indicators of muscle strength, balance, coordination, functional mobility, and quality of life. Results. Implementation of the program led to significant improvements in rehabilitation outcomes. Patients demonstrated measurable gains in lower limb muscle strength, enhanced postural control, improved coordination, and better walking parameters. Average gait speed increased by more than 20%, and step length and cadence became more symmetrical compared to baseline. In the 6-Minute Walk Test, patients extended their average walking distance from 260 m at baseline to 320 m after completing the program, indicating greater endurance. Balance performance also improved, with mean Berg Balance Scale scores rising from 42 to 48 points, reflecting more stable mobility. Functional mobility scores increased across all amputation levels, with transtibial amputees showing the most pronounced progress. Importantly, the structured protocol reduced rehabilitation duration by approximately 3 weeks on average and facilitated earlier adaptation to the prosthesis. Psychological support played a crucial role in helping patients overcome fear of falling, enhancing motivation, and promoting consistent use of the prosthesis in daily life. Overall, the combined multidisciplinary approach ensured higher mobility levels, faster reintegration into daily activities, and substantial improvements in self-reported quality of life across both physical and psychosocial domains. Conclusions. The proposed rehabilitation program proved effective for optimizing recovery after lower limb amputation. Its application in clinical practice can improve functional outcomes and quality of life and may be recommended for wider use in rehabilitation services.
PHARMACOGENETIC ASPECTS OF THERAPY FOR AUTOIMMUNE HEPATITIS AGAINST THE BACKGROUND OF DEGENERATIVE-DYSTROPHIC JOINT LESIONS.
(2025) Borysenko T. V.; Babalian V. O.; Dorofieieva V. R.; Danylchenko S. I.; Fedota О. М.
Introduction and aim. The pathogenesis of autoimmune diseases, including musculoskeletal, gastrointestinal, and endocrine manifestations, involves the interaction of genotype and environmental factors. Pathologies demonstrate comorbidity and clinical heterogeneity even within a single family. Genetic polymorphisms of one-carbon metabolism are key regulators of cel- lular processes that become therapeutic targets. Description of the case. The study describes personalized therapy for a patient with an autoimmune comorbid disease, with an emphasis on genetic and metabolic characteristics. The treatment regimen is adapted to the features of the one-carbon metabolism profile of a patient with chronic autoimmune hepatitis and degenerative-dystrophic joint disease. Family history includes autoimmune thyroiditis, vitiligo, Parkinson’s disease, cardiovascular diseases. The patient’s genotype for single nucleo- tide polymorphisms rs1801133, rs1801131, rs1801394, rs1805087, and rs3733890 of the one-carbon metabolism genes is asso- ciated with elevated plasma homocysteine levels. After treatment, changes in biochemical parameters were observed: alanine aminotransferase (72→53 U/L), aspartate aminotransferase (53→44 U/L), gamma-glutamyltransferase (129→89 U/L), alkaline phosphatase (313→125 U/L) and homocysteine (15.1→17.0 μmol/L). Conclusion. Positive dynamics after personalized therapy demonstrates the importance of an interdisciplinary approach to etio- pathogenetic treatment, emphasizing the need to support hepatobiliary function along with muscular and skeletal therapy.
PHYSICAL ACTIVITY AND REHABILITATION STRATEGIES IN THE COMPREHENSIVE MANAGEMENT OF TYPE 2 DIABETES
(2025) Voitenko D. O.; Golovchenko I. V.; Tarasova O. O.; Morozenko D. V.; Danylchenko S. I.
Type 2 diabetes mellitus is one of the most common non-communicable diseases worldwide and is linked to high risks of complications, disability, and reduced quality of life. Consequently, there is an increasing need for effective non-drug treatment options, especially physical rehabilitation and personalized physical activity. Aim. To summarize current scientific evidence on the role of physical activity and rehabilitation technologies in the comprehensive management of patients with Type 2 diabetes mellitus and to analyze the effectiveness of existing approaches considering clinical, functional, and age-related factors. Materials and Methods. An analytical review of 36 scientific publications from international databases (PubMed, Scopus, Web of Science) was conducted. The selected studies focused on the use of physical therapy in Type 2 diabetes mellitus, were of high methodological quality, and provided data on the effects of physical activity on metabolic, functional, and psycho-emotional indicators. Results. This article summarizes current approaches to the use of therapeutic exercise, kinesiotherapy, massage, hydrotherapy, diet therapy, and phytotherapy in the treatment of Type 2 diabetes mellitus. Special attention is given to the importance of individualized exercise programs based on disease compensation level, cardiovascular comorbidities, physical fitness, and coexisting conditions. It has been shown that moderate-intensity physical activity (60–75% HRmax) improves insulin sensitivity, reduces body weight, normalizes glycemia, and prevents complications. Emphasis is placed on the gradual increase in physical load, glycemic control before and after exercise, and the importance of psycho-emotional support. Conclusions. Integrating physical rehabilitation methods into the treatment of Type 2 diabetes mellitus significantly enhances therapy effectiveness, improves patients' quality of life, and reduces the risk of complications. A promising direction is the development of differentiated rehabilitation programs tailored to individual clinical and physiological characteristics.
PHYSICAL THERAPY IN GERONTOLOGY: OPPORTUNITIES FOR ENHANCING QUALITY OF LIFE AMID POPULATION AGEING
(2025) Khan A. Yu.; Tarasova O. O.; Danylchenko S. I.; Golovchenko I. V.; Morozenko D. V.
This review article examines current approaches to physical therapy in gerontological practice aimed at preserving functional independence and improving quality of life in adults aged 65 and older. Demographic trends toward an increasing proportion of older individuals present healthcare systems with new challenges, notably the prevention of non-communicable diseases, the reduction of fall risk, and the mitigation of rapid functional decline. Regular adaptive physical activity – including aerobic, resistance, balance, and yoga exercises – has been shown to significantly lower the risk of cardiovascular disease, osteoporosis, and type 2 diabetes, while also enhancing cognitive function and psycho emotional well-being (SMD (Standardized Mean Difference) ≈ 0.5 for cognitive reserve; SMD ≈ –0.6 for anxiety reduc- tion). Individualized exercise programs that combine aerobic and strength training yield sta- tistically significant improvements in functional status, reductions in depressive symptoms, and increases in self-esteem. A dedicated section addresses non-pharmacological modalities such as therapeutic massage, physical agents (galvanic current, electrophoresis, ultrasound, magnetotherapy), respiratory and inhalation techniques, short wave diathermy, and low am- plitude electrical stimulation. These interventions effectively relieve pain, improve microcir- culation, reduce muscle tension, and promote tissue healing in degenerative dystrophic con- ditions. Significant attention is given to emerging technologies – tele physiotherapy, wearable sensors, virtual reality, biofeedback, and transcranial magnetic stimulation which facilitate remote monitoring, personalize interventions, and expand rehabilitation access for individuals with limited mobility. A multidisciplinary team approach is essential for developing compre- hensive plans that address patients’ physical, cognitive, and psychosocial needs. The article concludes by emphasizing the need to integrate innovative physiotherapeutic strategies into primary care, strengthen the evidence base, and enhance professional training.
SENSORY INTEGRATION IN PEDIATRICS
(2025) Vlasov Ye. D.; Holovchenko I. V.; Danylchenko S. I.
The relevance of studying sensory integration in pediatrics cannot be overestimated in the modern world, where children's health and development are a priority for many parents, pediatricians, and society as a whole. Scientific research in the field of sensory integration helps to understand the nature of sensory disorders in children and their impact on development. They help to identify risk factors that may lead to the occurrence of such disorders, as well as effective methods of their diagnosis and treatment.
THE ROLE OF LACTATE IN THE BODY OF MARTIAL ARTISTS DURING PHYSICAL ACTIVITY: A NEW LOOK AT THE PROBLEM
(2025) Belenichev I. F.; Gunina L. M.; Orlov O. I; Samura I. B.; Doroshenko E. Yu.; Danylchenko S. I.; Skoryna D. Yu.; Бєленічев І. Ф.; Гуніна Л. М.; Орлов О. І.; Самура І. Б.; Дорошенко Е. Ю.; Данильченко С. І.; Скорина Д. Ю.
THE SYSTEM OF RISK FACTORS FOR DISEASES IN VALEOLOGICAL DISCIPLINES
(2024) Shevchenko A.S.; Shevchenko V.V.; Pomogaybo K.G.; Danylchenko S. I.; Brown G.W.; Shumskyi O. L.; Bilyi Ye.Ye.; Zhoga R.А.; Yushko V. I.
Background. With a view of primary prevention of diseases common in the world, medical workers and educators can effectively work together within teaching valeological disciplines at higher education institutions. Medical information should be adapted for non-medical students using the methods of scaling, aggregation, balancing and system analysis. Their application re- quires studying the content of main topics of valeological disciplines, determining the boundaries of didactic adaptation and testing in different higher education establishments. Adaptation of medical information on risk factors for understanding by non-medical students has not been stu- died enough. Aim. To study the characteristics and interrelationships of risk factors of socially significant diseases for the didactic adaptation of the content of valeological disciplines. Materials and Methods. The bibliosemantic method, comparative method, and system ana- lysis method were used for the study. The analysis takes into account the experience of primary prevention of diseases and teaching valeological disciplines in higher education institutions in Ukraine and Germany. Results and Conclusions. The system of risk factors for diseases that are responsible for a sig- nificant number of deaths in most countries of the world is the subject of study of modern valeo- logical disciplines. Medical research allows us to divide risk factors into controllable, conditio- nally controllable and uncontrollable. The impact of the first two groups of risk factors on health can be eliminated or significantly weakened by forming non-medical students’ valeological com- petence and adherence to a healthy lifestyle throughout life. The programs for primary prevention of socially significant diseases should include recommendations for quitting smoking, alcohol abuse, drug use, overeating, overfatigue, hypodynamia, or, conversely, extreme sports, and un- protected sex. Didactic adaptation of complex medical information is needed for valeological education of non-medical students. Its algorithms are analyzed in this article.
THE USE OF VIRTUAL REALITY (VR) AND AUGMENTED REALITY (AR) IN MEDICINE: AN OVERVIEW OF CURRENT APPROACHES AND PERSPECTIVES
(2025) Yashna P. O.; Antonov V. S.; Danylchenko S. I.
Introduction. Virtual Reality (VR) and Augmented Reality (AR) are opening new horizons in medicine by enabling the creation of interactive environments. VR simulates a fully artificial world where patients or medical professionals can practice skills or perform therapeutic tasks. AR places digital elements into the real world, enriching it with valuable information for diagnostics, training, or treatment. Recent studies demonstrate the effectiveness of VR and AR in surgery, rehabilitation, psychotherapy, and medical education.