Browsing by Author "Morozenko, D. V."

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COMPLEX REHABILITATION OF ISCHEMIC HEART DISEASE PATIENTS AFTER CORONARY BYPASS OPERATION WITH THE USE OF BIOLOGICALLY ACTIVE ADDITIVES
(2023) Horoshko, V. I.; Yashchyshyn, Z. M.; Danylchenko, S. I.; Morozenko, D. V.; Gliebova, K. V.; Kononenko, N. M.; Yeromenko, R. F.; Данильченко, С. І.
Aim: The purpose of the work was to study the possibility of using Dihydroquercetin in rehabilitation programs for patients with coronary artery disease after Coronary artery bypass grafting (CABG) surgery in order to increase the effectiveness of rehabilitation, which has notable scientific and practical significance. Materials and Methods: The methodological basis of the research is based on systemic, historical, terminological, and informational approaches. Results: The results of the study showed the high clinical effectiveness of Dihydroquercetin in the complex medical rehabilitation of patients with coronary artery disease who underwent the operation. The pill intake did not affect indicators of carbohydrate and lipid metabolism, which indicates its metabolic neutrality. None of the patients had any worsening of the condition, increased frequency of angina attacks, or episodes of painless ischemia. All patients indicated good tolerability of the drug, and improvement in general well-being (reduction or disappearance of shortness of breath, decrease in pain intensity, increase in activity, improvement in sleep). The implementation of the optimized rehabilitation program also contributed to the improvement of the psycho- emotional state of the patients. Conclusions: Сomplex medical rehabilitation of patients with coronary heart disease after Coronary artery bypass grafting surgery according to a program with the inclusion of Dihydroquercetin helps to improve the rheological properties of blood, strengthen the active vasomotor mechanisms of MC regulation, improve indicators of central and peripheral hemodynamics, blood oxygenation, increase in exercise tolerance, improve psycho-emotional the condition, which ultimately ensure an increase in the rehabilitation effect.
MATHEMATICAL MODELING OF THE STRESS-STRAIN STATE OF THE “BONE-IMPLANT” SYSTEM DURING THE OSTEOSYNTHESIS WITH A PHILOS WITH POLYLACTIC ACID IMPLANTS
(2020) Korzh, M. O.; Makarov, V. B.; Lipovsky, V. I.; Morozenko, D. V.; Danylchenko, S. I.; Данильченко, С. І.
The aim: To study was to use mathematical modeling in assessing the stress-strain state of the bone-implant system during plate osteosynthesis with a PHILOS plate of a proximal humerus fracture with polylactic acid implants. Materials and methods: Two bone-implant systems with a three-fragment humerus fracture according to the Neer classification (type 11-C1 according to the AO / ASIF classification) were selected for the study, one of which was with additional reinforcement of the head fragment with two polylactic acid implants (PLA – polylactide Ingeo™ Biopolymer 4032D). Sawbones (Europe AB, Malmö, Sweden) built the humeral model on 3D scanning of the composite model № 3404 of the left humerus. Results: A comparative analysis of the obtained results of mathematical modeling of the stress-strain state of the bone-implant systems showed that with given constraints (hand abduction to 90°), the use of two polylactic acid implants can reduce the stress in the plate and screws, respectively, by 11% and 6% . Conclusions: The use of polylactic acid implants during osteosynthesis of three- and four-fragment fractures of the proximal humerus, especially in the case of osteoporosis, allows providing for the reinforcement of metal structures and supporting of the articular surface without deterioration of fixation rigidity.
MORPHOLOGICAL CHARACTERISTICS OF KIDNEYS OF CATS WITH CHRONIC KIDNEY DISEASE
(2023) Morozenko, D. V.; Vashchyk, E. V.; Zakhariev, A. V.; Gliebova, K. V.; Danylchenko, S. I.
Chronic kidney disease (CKD) is the most common metabolic disease of domestic cats, and older cats are most often affected. The prevalence of CKD in cats exceeds that of dogs, and the frequency of diagnosis of CKD in cats has increased in recent decades. Typical histologic features include interstitial inflammation, tubular atrophy, and fibrosis with secondary glomerulosclerosis. Thus, it can be considered relevant to study the morphology of the kidneys of cats with CKD in order to establish a complex of changes in the tubules and glomeruli of the kidneys with the aim of a clearer understanding of the clinical and pathogenetic mechanisms of the development of nephropathies.